http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-19990086271-A
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-39 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-22 |
classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-91 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-22 |
filingDate | 1998-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 1999-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-19990086271-A |
titleOfInvention | Novel endonucleases of immune cells and immunoadjuvant using the same |
abstract | The present invention relates to endonucleases, human B-lymphocytes that generate about 10 bp of single-stranded oligonucleotides with CpG motifs that are secreted from immune cells and recognize and process bacterial DNA as foreign substances and are involved in immune responses. Said endonuclease comprising culturing an IM9 cell line or a myeloid U937 cell line treated with TPA in a medium suitable for producing endonucleases and purifying endonucleases synthesized and secreted from said immune cells from this culture. The present invention relates to a preparation method of an agent and an immunoadjuvant comprising about 10 bp single-chain oligonucleotide having a CpG motif formed by treating bacterial DNA with the endonuclease of the present invention. |
priorityDate | 1998-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 435.