http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-19990077068-A
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1272 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-87 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-88 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7088 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-127 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-88 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 |
filingDate | 1997-01-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 1999-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-19990077068-A |
titleOfInvention | Nucleic Acid Delivery Methods and Compositions Used Therein |
abstract | (I)n n n w… x-y-NH-CH 2 -CH 2 O-R 5 (II)n n n The present invention relates to a method of introducing a nucleic acid into a cell. The method comprises a cell having a chain length corresponding to a compound of formula (I) wherein w is a nucleic acid, x is a non-amino acid or a non-peptide nucleic acid binding group, y is absent or corresponds to 1-30 carbon-carbon single covalent bonds. Is a spacer, R 4 is H, halogen or CH 2 OR 3 ; R 1 , R 2 , R 3 are the same or different and are hydrogen, methyl, ethyl, alkyl, alkenyl, hydroxylated alkyl, hydroxylated Saturated or unsaturated acyl groups derived from fatty acids having an alkenyl group or an alkyl, alkenyl, hydroxylated alkyl or hydroxylated alkenyl group comprising an ether and optionally having a carbon chain of 3-24 carbon atoms. At least one of R 1 , R 2 or R 3 comprises a saturated or unsaturated group having a carbon chain of 3-24 carbon atoms, or a compound of formula (II), wherein w is a nucleic acid and x is a non-amino acid Or a non-peptide nucleic acid binding group, y is absent or 1-30 carbon-carbon With a spacer having a chain length corresponding to a single covalent bond, R 5 is alkyl, alkenyl, hydroxy Chemistry alkyl, hydroxy stylized or alkenyl group, or an alkyl, alkenyl, hydroxy containing etherified An alkyl or hydroxylated alkenyl group, optionally a saturated or unsaturated acyl group having a carbon chain of 3-24 carbon atoms, R 5 comprises a group having a saturated or unsaturated carbon chain of 3-24 carbon atoms )). The invention also relates to such compounds. |
priorityDate | 1996-01-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 262.