| abstract |
In patients in need of treatment for a disease characterized by overexpression of cytidine deaminase or deoxycytidine deaminase, a method of treating the disease is disclosed. The method is a compound of Formula I:n n n (Ⅰ)n n n Wherein X and X 1 are each independently C or N;n n n R 1 is lower alkyl group, lower alkenyl group, lower alkynyl group, halogen or haloalkyl group; Andn n n R 2 is H, —N 3 , —OH, an amino group or a halogen)n n n Or administering a pharmaceutically acceptable salt thereof to the patient in an amount effective to treat the disease.n n n Pharmaceutical prescriptions useful in the methods of the invention are also disclosed. |