| abstract |
The present invention relates to compounds of formula (I)n n n Formula In n n n n n n n Wheren n n R 1 is phenyl, naphthyl, benzoxazoloyl, indolyl, indolonyl, benzimidazolyl, quinolyl, furyl, benzofuryl, thienyl, benzothienyl, oxazolyl or benzoxazolyl;n n n R 2 is H or (C 1 -C 6 ) alkyl;n n n R 3 is phenyl, pyridinyl, pyrimidinyl, pyrazinyl or pyridazinyl;n n n X is O, S, SO, SO 2 , NR 4 , C═O, CH (OH), CHR 4 ,n n n ego;n n n m is 0, 1 or 2;n n n n is 0, 1 or 2.n n n Compounds of the invention are ligands for the dopamine receptor subtype, in particular the dopamine D 4 receptor, and are therefore useful for treating disorders of the dopamine system. |