http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-19990075172-A
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 |
filingDate | 1998-03-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 1999-10-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-19990075172-A |
titleOfInvention | Method for preparing 7-halo-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro- [1.8] naphthyridine-3-carboxylate |
abstract | The present invention is characterized by reacting a compound of formula (2) with triethyl orthoformate and acetic anhydride in one reactor to obtain an enol ether, which is substituted with cyclopropyl amine, and then cyclized in the presence of a base. A method for effectively preparing a compound of formula 1, which is an intermediate of antibiotics:n n n Formula 1n n n n n n n n Formula 2n n n n n n n n Wherein R represents methyl, ethyl, propyl, iso-propyl, n-butyl, t-butyl, iso-butyl or allyl, and X represents fluorine, chlorine or bromine. |
priorityDate | 1998-03-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 60.