| abstract |
Methods of preparing novel LH-RH antagonists, particularly analogous peptides and side-chain modified peptides, salts thereof with pharmaceutically acceptable acids, and LH-RH antagonists and their salts are described. The peptides described herein are homologues of luteinizing hormone-releasing hormone (LH-RH). The compounds described herein have a high antagonistic potency and do not have undesirable side effects, especially edema inducing effects. |