http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-19990062826-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-4858 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-13 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-107 |
| filingDate | 1998-12-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1999-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-19990062826-A |
| titleOfInvention | Cyclosporine-containing pharmaceutical composition |
| abstract | The present invention relates to a pharmaceutical composition containing cyclosporin as an active ingredient. The composition according to the invention comprises, as its components, cyclosporine, triacetin or triethyl citrate as a cosurfactant alone or a mixture of both and a mixture of propylene carbonate, an oil component, and a surfactant. According to the present invention, an O / W type microemulsion having a particle diameter of 100 nm or less can be obtained when dissolved in water by appropriately adjusting the composition ratio of components. The composition of the present invention can be formulated as a soft capsule, a hard capsule with the junction sealed with gelatin bending, or an oral solution. In particular, when the composition of the present invention is formulated with a soft capsule, it provides an excellent advantage in changing the appearance of the capsule caused by gelatin membrane permeation of the solvent, suppressing the precipitation formation of the drug due to volatilization of the solvent, and economic effects by reducing the manufacturing cost. It is characterized by. |
| priorityDate | 1997-12-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 73.