http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-19990039173-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-1833 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-70 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-51 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 |
| filingDate | 1997-11-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1999-06-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-19990039173-A |
| titleOfInvention | Variants of the Protease of Hepatitis C Virus and Methods for Producing the Same |
| abstract | The present invention relates to a fusion protease in which a nonstructural protein 4A of hepatitis C virus (hereinafter abbreviated as "HCV") is bound to an amino terminal of a nonstructural protein 3 as opposed to the HCV genome sequence, and a method for preparing the same. will be. More specifically, the present invention provides a protease protein in which a portion of nonstructural protein 4A involved in the activation of protease is fused to the amino terminus of nonstructural protein 3, as opposed to the genome sequence of HCV, an amino acid sequence thereof, and an encoding thereof. The present invention relates to a base sequence and an expression vector capable of producing the recombinant protein in Escherichia coli and a method for producing a fusion protease derived from HCV in Escherichia coli, wherein the protease of the present invention is useful for protein structure formation. As it contains only a part of non-structural protein 4A, its size is small and easy to purify. Since non-structural protein 4A is more adjacent to the amino terminus of non-structural protein 3, its activity is increased, which is useful for screening and screening proliferation inhibitors of HCV. Can be used. |
| priorityDate | 1997-11-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 175.