http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-19990036110-A
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D409-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-12 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D409-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4025 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-401 |
filingDate | 1996-07-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 1999-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-19990036110-A |
titleOfInvention | 4-mercaptopyrrolidine derivatives as farnesyl transferase inhibitors |
abstract | The present invention relates to inhibitors of lasfarnesylation of compounds of formula (I) Or -SS-dimer when R 2 is H; Or an enantiomer, an optical isomer, a pharmaceutically acceptable salt, a drug precursor or a solvate thereof, and a pharmaceutically acceptable diluent or carrier, for the manufacture of a medicament for the treatment of cancer,n n n Formula In n n n n n n n Wherein R < 1 > is as defined for example in H and further in the specification; R < 2 > is, for example, H and further as defined in the specification; R < 3 > is H or a substituent having the meaning as defined in the specification; p is 0 to 3, which R 3 may be the same or different; L is a connecting portion, for example, -CO-NH 2 - and the meaning defined in the specification and in more; A is phenyl; Naphthyl; Membered monocyclic or bicyclic heteroaryl ring containing up to 5 heteroatoms individually selected from O, N and S. |
priorityDate | 1995-08-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 401.