| abstract |
The present invention provides a selective 5-HT 1A antagonist of formula (I) as first component (a), a 5-HT reuptake inhibitor, and (R) -enantiomer, in the form of a free base or a pharmaceutically acceptable salt thereof. A mixture of phosphorus second component (b), a preparation thereof, a pharmaceutical formulation comprising the mixture, uses and methods for the treatment of emotional disorders such as depression, anxiety and OCD by the mixture, and kits comprising the mixture It is about.n n n Formula In n n n n n n n Wherein R 1 is n-propyl or cyclobutyl; R 2 is isopropyl, tertiary butyl, cyclobutyl, cyclopentyl or cyclohexyl; R 3 is hydrogen; R 4 is hydrogen or methyl. |