http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-19980702048-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-1013 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-1005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-103 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| filingDate | 1996-02-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1998-07-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-19980702048-A |
| titleOfInvention | Novel Farnesyl Transferase Inhibitors, Preparations thereof, and Pharmaceutical Compositions Containing the Same |
| abstract | Novel farnesyl transferases of formula (1), methods for their preparation and pharmaceutical compositions containing them.n n n In Formula 1, R 1 is YSA 1- (Y is a hydrogen atom, an amino acid residue, a fatty acid residue, an alkyl or alkoxycarbonyl radical or R 4 is a phenyl radical or a radical of formula 2 (A 1 , X 1 , Y in Formula 2) 1 , R 2 , R ' 2 , X 2 , Y 2 , X, R 3 , R' 3 and R are as defined in formula (I). R 4 -which is a C 1-6 alkylradical optionally substituted by SA 1 , A 1 is an optionally alpha-substituted C 1-4 alkylene radical in the C (X 1 ) (Y 1 ) group by an amino, alkylamino, alkanoylamino or alkoxycarbonylamino radical; X 1 and Y 1 are each hydrogen or together with the carbon atom to which they are attached form a C═O group; R 2 is a C 1-4 alkyl radical optionally substituted by a cyclohexyl radical; R ' 2 is hydrogen or alkyl; X 2 and Y 2 are each a hydrogen atom or together with the carbon atom to which they are attached form a C═O group; R 3 is hydroxy, alkoxy, bots, captopril, alkylthio, the alkyl radical is optionally substituted alkyl sulfinyl, or alkyl sulfonyl and sulfonic optionally substituted C 1-4 alkyl radical, by the end, when R 3 a hydroxy radical, R 3 Can form lactones with alpha-carboxyl radicals; R ' 3 is hydrogen or alkyl; X is oxygen or sulfur atom; R is a hydrogen atom or an optionally substituted alkyl radical or an optionally substituted phenyl radical. The new product has anticancer properties.n n n Formula 1n n n n n n n n Formula 2 |
| priorityDate | 1995-02-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 120.