http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-19980077324-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-76 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6803 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-573 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-535 |
| filingDate | 1997-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1998-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-19980077324-A |
| titleOfInvention | Searching for antagonists that bind proteins containing SH2 sites involved in cell signaling |
| abstract | The present invention relates to a method of searching for an antagonist acting on an SH2 site by using a protein comprising an SH2 site that binds to alkaline phosphatase (AP). Specifically, the present invention is a fusion protein (hereinafter abbreviated as Ap-SrcSH2 fusion protein) that combines a protein containing an SH2 site involved in cell signaling process with alkaline phosphatase, which can be produced in large quantities in E. coli. The present invention relates to a method for preparing a vector, an AP-SH2 fusion protein, and an antagonist that acts on an SH2 site using alkaline phosphatase. Modulators and the like that act on the delivery process can be effectively screened. |
| priorityDate | 1997-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 142.