http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-19980076688-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C239-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-165 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C239-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-16 |
| filingDate | 1997-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1998-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-19980076688-A |
| titleOfInvention | Novel compounds having ACAT inhibitory activity, preparation methods thereof, and compositions comprising the same |
| abstract | The present invention relates to a novel compound represented by the following formula (1) having an ACAT (acyl coei: cholesterol acyltransferase) inhibitory activity, a preparation method thereof, and a composition comprising the same, wherein the compound of the present invention esterifies cholesterol to the body It effectively and strongly inhibits the activity of ACAT, an enzyme that promotes cholesterol accumulation, has excellent water-solubility, and is easy to synthesize, which is useful for the prevention and treatment of cardiovascular diseases such as hyperlipidemia, coronary heart disease, arteriosclerosis, and myocardial infarction. Can be used.n n n [Formula 1]n n n n n n n n (Wherein X, R 1 , R 2 , R 3 , R 4 and R 5 are as defined in the specification). |
| priorityDate | 1997-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 82.