http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-19980069782-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D309-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C67-02 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D309-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D309-10 |
| filingDate | 1997-06-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1998-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-19980069782-A |
| titleOfInvention | Methods for preparing simvastatin from lovastatin or mesylonic acid |
| abstract | The method comprising the steps of opening the pyranone ring by treatment with lovastatin and cyclopropylamide or butylamide, adding the methyl group to the 2-methylbutyrate side chain, and closing the open pyrenone ring to form simvastatin < / RTI > wherein the simvastatin salt is prepared from lovastatin or mevinolinic acid.n n n The present invention is practiced without the need to protect and deprotect the two hydroxyl groups of the open pyranone ring. The starting material is treated with cyclopropylamine and simvastatin is prepared via novel intermediate, lovastatin cyclopropylamide. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100502833-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100361833-B1 |
| priorityDate | 1997-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 68.