http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-19980039641-A
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D231-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D233-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D249-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-50 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D521-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-506 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-14 |
filingDate | 1996-11-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 1998-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-19980039641-A |
titleOfInvention | 4,5-diamino pyrimidine derivatives and preparation method thereof |
abstract | The present invention provides novel 4,5-diamino pyrimidine derivatives of the general formula (I) having a inhibitory action on cyclic guanosine 3 ′, 5′-monophosphate phosphodiesterase and physiologically acceptable thereof To salts, solvates or metabolic esters which are susceptible to conversion and processes for their preparation:n n n n n n n n Wherein X is a bond, C 1-4 alkylene, C 1-4 alkyleneoxy, C 1-4 alkoxyphenyl or phenyl (C 1-4 ) alkylene; Y is a bond or C 1-2 alkyl; R 1 is (i) 5 to 15 branched-chain or ring-linked hetero compounds optionally containing one or two elements of nitrogen, oxygen or sulfur, hydrogen, halogen, nitro, hydroxy, C 1-6 alkyl, C Substituted with one or two groups selected from 3-6 alkenyl and halogen C 1-4 alkoxy, or (ii) a C 4-10 carbocyclic cyclic compound or (iii) a hydroxy (C 1-4 alkoxy) group; R 2 is a 5 to 15 side chain or ring heterocyclic compound in which nitrogen, oxygen or sulfur optionally contains one or two elements, hydrogen, hydroxy, halogen, nitro, hydroxy (C 1-5 ) alkyl, Substituted with one or two groups selected from C 1-6 alkyl, C 3-6 alkenyl and halogen C 1-4 alkoxy; R 3 is hydrogen, or R 4 and R 5 are each independently (i) hydroxy, C 1-6 alkyl, C 3-7 cycloalkyl, C 3-6 alkenyl, halogen C 1-6 alkyl, halogen C 2-6 al A group selected from kenyl and C 1-4 alkoxy or (ii) And R 6 is a group selected from hydrogen, hydroxy, C 1-6 alkyl, C 3-6 alkenyl, halogenC 1-6 alkyl, halogen, nitro and C 1-4 alkoxy. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100546992-B1 |
priorityDate | 1996-11-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 125.