http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102468480-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2300-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-337 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4985 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4745 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06 |
| filingDate | 2019-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-102468480-B1 |
| titleOfInvention | Novel compounds for enhancing anti-cancer activity and pharmaceutical composition thereof |
| abstract | The present invention relates to a novel compound and a pharmaceutical composition for enhancing anti-cancer activity containing the same, and more particularly, by including a compound represented by the following formula (1) or a pharmaceutically acceptable salt thereof, the anti-cancer activity of an anti-cancer agent or radiation It can promote cancer cell proliferation inhibition and induce apoptosis, etc. to effectively treat cancer: [Formula 1] In Formula 1, n is an integer from 0 to 4; R 1 is hydrogen, C1 to C10 alkyl or aryl(C1 to C4)alkyl; R 3 is C1 to C6 alkyl, and when the R 3 is plural, they are the same as or different from each other; L 1 is a direct bond or C1 to C6 alkylene; R 2 is hydrogen, C1 to C10 alkyl or aryl (C1 to C4) alkyl, R 4 is hydrogen, C1 to C4 alkyl, C3 to C8 cycloalkyl or aryl (C1 to C4) alkyl; R 2 and R 4 form a 4- to 7-membered ring and are connected to each other; The alkyl of R 1 to R 4 , the arylalkyl of R 1 , R 2 and R 4 , the cycloalkyl of R 4 , and the alkylene of L 1 are each independently a C1 to C6 alkyl group, a halo group, or an aryl group. group, a haloalkyl group, a nitro group, a cyano group, an alkylthio group, or an arylalkylthio group unsubstituted or substituted with a substituent, and when substituted with a plurality of substituents, they are the same as or different from each other. |
| priorityDate | 2018-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 295.