http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102459434-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23V2002-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23V2200-316 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23L33-105 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K36-73 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23K20-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23K10-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K36-704 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K36-70 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-73 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A23K10-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A23K20-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A23L33-105 |
| filingDate | 2020-07-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-102459434-B1 |
| titleOfInvention | Composition for improvment, prevention or treatment in muscular atrophy comprising extracts of Potentilla chinensis or Indigo |
| abstract | The present invention relates to a composition for improving, preventing, or treating muscle atrophy, and more particularly, to a composition for improving, preventing or treating muscle atrophy containing an extract of Wireungchae or indigo plant. The composition containing the Wireungchae extract or the indigo plant extract of the present invention as an active ingredient is effective in improving muscle atrophy by inhibiting the overexpression of Atrogin1 and MuRF1, which are ubiquitin ligases, and inhibiting the activity of the muscle atrophy regulator Forkhead box (FOX) 0 to perform In addition, the composition containing the Wireungchae extract or the indigo plant extract of the present invention as an active ingredient suppresses myostatin, which is involved in the inhibition of muscle tissue production, and increases follistatin, an inhibitor of myostatin, through It can strengthen muscle, increase the size of myotube, and inhibit the activity of histone deacetylases (HDACs). In addition, the composition containing the extract of Wireungchae or indigo plant of the present invention as an active ingredient is suberoylanilide hydroxamic acid (SAHA, HDAC inhibitor), which is known to be effective in improving muscle atrophy and strengthening muscles, It may be more effective than ursolic acid or creatine monohydrate. |
| priorityDate | 2020-07-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 335.