http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102412045-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-437 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-02 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-437 |
| filingDate | 2015-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-102412045-B1 |
| titleOfInvention | Hydrazide compound as blood coagulation factor xa inhibitor |
| abstract | The present invention relates to a compound having the structure of formula (I), or a pharmaceutically acceptable salt thereof, (I) wherein X is selected from a 3-9 membered carbocyclic ring or a benzo ring thereof, a 4-10 membered heterocyclic ring or a benzo ring thereof; Y, Z are each independently selected from a 4-9 membered saturated heterocyclic ring; R 1-3 are each independently selected from H, F, Cl, Br, I, CN, OH, SH, NH 2 , CHO, COOH, or optionally substituted by R 01 C 1-10 alkyl or hetero alkyl, C 3-10 cyclohydrocarbyl or heterocyclohydrocarbyl , C 3-10 cyclohydrocarbyl or C 1-10 alkyl or heteroalkyl substituted by heterocyclohydrocarbyl. The compound of the present invention can be used as an anticoagulant for the treatment and prevention of thromboembolic disorders, and the present invention can satisfy the actual demand for a selective inhibitor of blood clotting factor Xa by providing a potent inhibitor of blood clotting factor Xa. |
| priorityDate | 2014-05-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 425.