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filingDate 2020-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2022-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2022-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-102408166-B1
titleOfInvention Biosensing chip to analyze cell-derived materials during cell culture, and method for quantitative analysis of cell activity using the same
abstract The present invention is a sensor chip for cell-derived analysis capable of quantitatively analyzing cell activity by electrochemically measuring the concentration of hydrogen peroxide, which is secreted according to the activity of immune cells, and quantitative analysis of cell activity using the same To a method, the sensor chip for analyzing a cell derivative of the present invention includes an upper plate having a first groove and a second groove forming a culture space for culturing immune cells together with the first groove, the upper plate and A culture unit having a combined lower plate, coupled to the upper plate so as to extend from the outside of the culture space to the inside of the culture space, and horseradish peroxidase (HRP) is fixed to one end positioned inside the culture space A working electrode formed with a reduced portion made of a carbon paste, one end coupled to the upper plate so as to be located inside the culture space, an auxiliary electrode spaced apart from the working electrode, and disposed between the upper plate and the lower plate, one end The additional includes a reference electrode positioned inside the culture space.
priorityDate 2020-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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