| abstract |
The present invention is a compound of general formula (I), wherein one of X 1 and X 2 represents N, the other of X 1 and X 2 represents —C(CH 3 ) and A is unsubstituted or substituted 5-, 6- or 10-membered aryl or heteroaryl, n is 0 or 1, and B is a bicyclic heteromoiety as defined herein. The compounds are inhibitors of phosphodiesterase 10A and may find use as medicine in the treatment of diseases and disorders of psychotic, neurological and cognitive functions. (I) |