http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102398990-B1
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-03 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-0276 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5088 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-027 |
filingDate | 2020-03-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2022-05-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2022-05-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-102398990-B1 |
titleOfInvention | Nkx3.1 gene knock-out genitourinary disease animal model and use thereof |
abstract | The present invention relates to an animal model of urogenital disease in which the Nkx3.1 gene is knocked out and uses thereof. The present invention confirmed that stable production of a transgenic urogenital disease animal model having a desired phenotype is possible by using TALEN with low non-specific mutation efficiency and knocking out the Nkx3.1 gene through manipulation of a rat fertilized egg. The transgenic animal model can be applied to a variety of urogenital disease research, such as diagnosis, prognosis and metastasis of urogenital diseases including prostate cancer and breast cancer, and screening of candidate drugs for urogenital diseases. expected to have |
priorityDate | 2020-03-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 98.