http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102398990-B1

Outgoing Links

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classificationCPCAdditional http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-075
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-03
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-0276
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5088
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-027
filingDate 2020-03-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2022-05-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2022-05-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-102398990-B1
titleOfInvention Nkx3.1 gene knock-out genitourinary disease animal model and use thereof
abstract The present invention relates to an animal model of urogenital disease in which the Nkx3.1 gene is knocked out and uses thereof. The present invention confirmed that stable production of a transgenic urogenital disease animal model having a desired phenotype is possible by using TALEN with low non-specific mutation efficiency and knocking out the Nkx3.1 gene through manipulation of a rat fertilized egg. The transgenic animal model can be applied to a variety of urogenital disease research, such as diagnosis, prognosis and metastasis of urogenital diseases including prostate cancer and breast cancer, and screening of candidate drugs for urogenital diseases. expected to have
priorityDate 2020-03-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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