http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102393786-B1

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filingDate 2018-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2022-05-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2022-05-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-102393786-B1
titleOfInvention Method for purifying polyethylene glycol having one carboxyl group
abstract To provide an industrially feasible purification method for a polyethylene glycol compound having one carboxyl group in which wastes such as adsorbents and ion exchange resins are not produced with good efficiency and purity. As an aqueous solution of a polyethylene glycol compound, the aqueous solution whose pH is 8-11 is prepared. The aqueous solution and the mixed organic solvent are mixed at a temperature of 15°C or higher and 50°C or lower to separate the organic layer and the aqueous layer. The ratio of the organic solvent I in the mixed organic solvent is 25-60 mass %, and the ratio of the organic solvent II is 75-40 mass %. Organic solvent I is a hydrocarbon solvent selected from toluene, xylene, etc., and the organic solvent II is a halogenated hydrocarbon solvent selected from chloroform and the like, and the mixing ratio of organic solvent I to organic solvent II (organic solvent I/organic) Solvent II) Y, temperature T (°C), and the weight average molecular weight M of the polyethylene glycol compound satisfy the relationship of 3.11×10 -6 M+0.084≦Y-0.0135T≦-1.77×10 -6 M+0.404.
priorityDate 2017-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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