http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102381610-B1
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2800-108 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-121 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-20 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-905 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-81 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-102 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-90 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-81 |
filingDate | 2015-07-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2022-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2022-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-102381610-B1 |
titleOfInvention | Genetic targeting in non-conventional yeast using an rna-guided endonuclease |
abstract | Disclosed herein are unconventional yeast comprising at least one RNA-directed endonuclease (RGEN) comprising at least one RNA component without a 5'-cap. Such uncapped RNA components comprise sequences complementary to target site sequences of chromosomes or episomes in yeast. The RGEN is capable of binding and optionally cleaving one or both DNA strands of sequence at the target site. An example of an RGEN herein is a complex of a Cas9 protein and a guide RNA. In certain embodiments a ribozyme is used to provide an RNA component that lacks a 5'-cap. Methods of targeting genes in unconventional yeast are further disclosed. |
priorityDate | 2014-08-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1615.