| abstract |
The present invention relates to a pharmaceutical composition or a health functional food for preventing, improving or treating sleep disorders, comprising an Artemisia capillaris extract as an active ingredient, wherein the Artemisia capillaris extract encodes enzymes related to melatonin synthesis By increasing the production of melatonin by significantly increasing the expression of Tph1a (tryptophan hydroxylase 1a), Aanat1 (arylalkylamine-N-acetyltransferase 1), Aanat2 (arylalkylamine-N-acetyltransferase 2), and Hiomt (hydroxyindole-O-methyltransferase), Artemisia capillaris extract is provided as an effective agent for preventing, improving, or treating sleep disorders. |