Predicate |
Object |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-31 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-92 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-73 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-732 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-51 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-515 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-468 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2863 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 |
filingDate |
2017-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2022-02-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate |
2022-02-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
KR-102360742-B1 |
titleOfInvention |
Bispecific antibodies targeting EGFR and HER2 |
abstract |
The present disclosure relates to bispecific antibodies targeting EGFR and HER2, and methods of producing these antibodies. Bispecific antibodies consist of one complete antibody in which two VH-VL chains are attached via a linker to each N-terminal region of both VH chains of the antibody. The constructed bispecific antibody utilizes the amino acid sequences of the heavy (VH) and light (VL) chain variable regions of two monoclonal antibodies targeting EGFR and HER2, cetuximab and trastuzumab, respectively. |
priorityDate |
2016-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |