http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102354963-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-13 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D215-233 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D215-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-47 |
| filingDate | 2015-02-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-01-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-01-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-102354963-B1 |
| titleOfInvention | Crystalline solid forms of n-[4-[(6,7-dimethoxyquinolin-4-yl)oxy]phenyl]-n'-[4-fluorophenyl) cyclopropane-1,1-dicarboxamide, processes for making, and methods of use |
| abstract | The present invention relates to the chemical compound N-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]phenyl}-N'-(4-fluorophenyl)cyclopropane-, useful for the treatment of cancer It relates to a novel crystalline solid form of 1,1-dicarboxamide (Compound 1), a solvate comprising a hydrate thereof. In addition, pharmaceutical compositions comprising said crystalline solid form and methods for preparing said crystalline solid form, as well as methods of using them for the treatment of cancer, in particular thyroid cancer, prostate cancer, hepatocellular carcinoma, renal cancer and non-small cell lung cancer has been disclosed. The crystalline solid form can be used to prepare the L-malate salt of caboxantinib. |
| priorityDate | 2014-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 49.