Predicate |
Object |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-90 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-92 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-565 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-39 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-04 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
filingDate |
2017-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2022-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate |
2022-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
KR-102354845-B1 |
titleOfInvention |
Humanized anti-CLEVER-1 antibodies and uses thereof |
abstract |
The present invention relates to an agent capable of binding to human CLEVER-1 and recognizing an epitope of CLEVER-1 and a humanized antibody or single chain Fv or Fab fragment, wherein the epitope is discontinuous and comprises the sequences PFTVLVPSVSSFSSR and QEITVTFNQFTK. The present invention also relates to agents capable of binding to an epitope of human CLEVER-1 for use in abrogating tumors or antigen-induced immunosuppression. The invention also relates to a pharmaceutical composition comprising an agent capable of binding to human CLEVER-1 and a suitable excipient. |
priorityDate |
2016-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |