http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102345012-B1
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-50 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-635 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-635 |
filingDate | 2021-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-102345012-B1 |
titleOfInvention | Method for production of human parathyroid hormone 1-34 with groes pusion |
abstract | One embodiment of the present invention relates to a fusion tag, a fusion polypeptide comprising the fusion tag and human parathyroid hormone 1-34. When the novel fusion tag according to the present invention is used, the yield of human parathyroid hormone 1-34 can be improved compared to the conventional fusion tag. In particular, it is useful in the case of producing human parathyroid hormone 1-34 having a relatively small molecular weight and easily degraded amino terminus using genetic recombination technology. In addition, the fusion polypeptide containing the fusion tag according to an embodiment of the present invention is protected from proteolytic enzymes of the host cell by inducing expression in the form of an inclusion body in the host cell, thereby stably producing human parathyroid hormone 1-34. There are advantages to producing. Therefore, it is possible to provide a method for producing human parathyroid hormone 1-34 with improved stability and yield compared to the case of using a conventional fusion tag. |
priorityDate | 2019-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1383.