http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102341660-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2300-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4965 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-5377 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0053 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4965 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5377 |
| filingDate | 2017-09-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-102341660-B1 |
| titleOfInvention | A therapeutic combination comprising a RAF inhibitor and an ERK inhibitor |
| abstract | The present invention provides a composition comprising (a) at least one ERK inhibitor, preferably Compound B, and (b) a c-RAF inhibitor or a pharmaceutically acceptable salt thereof, preferably Compound A, as described herein. Combination therapy, which may be combined into a single agent composition, or prepared for separate or sequential administration. It includes c-RAF inhibitors and ERK inhibitors formulated for simultaneous, separate or sequential administration to treat proliferative diseases, particularly advanced solid tumors carrying mitogen-activated protein kinase (MAPK) modifications, Commercial packages containing the combination as well as methods of using the compounds in combination are included. |
| priorityDate | 2016-09-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 120.