| abstract |
The present invention provides a quinazoline derivative represented by the following formula (I), or a pharmaceutically acceptable salt thereof: wherein R 1 and R 2 represent a hydrogen atom, a halogen atom, or a lower alkyl group optionally having a substituent; Z represents a cycloalkyl group having a substituent or a cycloalkenyl group having a substituent; Q represents a bicyclic heteroaryl group optionally having a substituent. The compound has an inhibitory effect on the Wnt/β-catenin signaling pathway, exhibits an antitumor effect, and is useful as a medicament. |