| abstract |
The present invention relates to a novel AS-DK143 compound, and to a pharmaceutical composition comprising AS-DK143 or a pharmaceutically acceptable salt thereof, and mPEG-PLA as a carrier, for the treatment of cancer. Specifically, in the present invention, since the anticancer drug DK-143 is poorly soluble, a new compound is synthesized by binding aspirin to DK-143 as a method to overcome this. This compound has a synergistic effect as an anticancer drug, the compound When the nanoparticles are prepared by loading mPEG-PLA, the water solubility and bioavailability of the compound are improved, so that the anticancer effect of the compound on solid cancer can be improved. |