| abstract |
The present invention relates to pharmaceutical agents useful for therapeutic and/or prophylactic methods in mammals, specifically NF-κB inducible kinase (NIK or MAP3K14 also known as NF-κB-inducible kinase useful for the treatment of diseases such as cancer, inflammatory diseases, metabolic diseases and autoimmune diseases. There are) inhibitors. The present invention also relates to pharmaceutical compositions comprising such compounds, methods for preparing such compounds and compositions, and to treat diseases such as cancer, inflammatory diseases, metabolic diseases such as obesity and diabetes, and autoimmune diseases. It relates to the use of such compounds or pharmaceutical compositions for treatment or prophylaxis. |