http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102303154-B1
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2300-00 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-551 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4985 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4985 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-551 |
filingDate | 2019-11-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-102303154-B1 |
titleOfInvention | A pharmaceutical composition for treating stroke containing sildenafil and Rho-associasted kinase inhibitor |
abstract | The present invention relates to a pharmaceutical composition for the treatment of stroke comprising a phosphodiesterase type 5 inhibitor and a ROCK inhibitor (Rho-associasted kinase inhibitor), and more specifically, to a pharmaceutical composition comprising sildenafil and GSK429286A. , to a pharmaceutical composition for treating brain damage due to stroke. The present inventors studied the combination of sildenafil and a ROCK inhibitor for stroke treatment based on clinical knowledge related to stroke treatment. As it was confirmed for the first time that the size of brain damage due to stroke is significantly reduced compared to that, the pharmaceutical composition according to the present invention can be usefully used not only for the treatment of stroke but also for the study of various ischemic cerebrovascular diseases including ischemic stroke. is expected to |
priorityDate | 2019-11-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 59.