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filingDate 2020-01-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2021-09-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2021-09-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-102299769-B1
titleOfInvention Manufacturing method of liposome with enhanced skin permeation
abstract The present invention relates to a method for producing a liposome, comprising the steps of preparing an aqueous phase component and an oil phase component, preparing a mixed solution by mixing the aqueous phase component and the oil phase component, and emulsifying the mixed solution to prepare liposomes, , The aqueous phase component includes a charge stabilizer, the oil phase component includes a membrane softener, the aqueous phase component or oil phase component includes an active ingredient, and the charge stabilizer is a triple block consisting of a block of hydrophilic-lipophilic-hydrophilic groups. As a tri-block copolymer, HLB (Hydrophilic Lipophilic Balance) is 15 to 29, and the membrane softener is an amphoteric polymer consisting of a block of hydrophilic-lipophilic groups, and HLB (Hydrophilic Lipophilic Balance) is 10 or more. .
priorityDate 2020-01-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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