http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102294544-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23V2002-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K36-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23L33-105 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7034 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P13-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A23L33-105 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7034 |
| filingDate | 2019-05-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-102294544-B1 |
| titleOfInvention | Pharmaceutical composition for preventing and treating prostate disease, comprising the compound isolated from Platycodon grandiflorum and Platycodon grandiflorum extract as an active ingredient |
| abstract | The present invention relates to a bellflower (Platycodon grandiflorum) extracts, fractions and derivatives of discrete active compound obtained in the manner as in Production therefrom extract, fraction or prostate disease preventive and therapeutic pharmaceutical composition comprising the isolated active compound thereof, The present invention confirmed that (1) hot water of bellflower, 30% alcohol, and 100% alcohol extract had no cytotoxicity against human prostate stromal cells (WPMY-1) and human prostate cancer cell lines (LNCap, PC-3), (2) It was confirmed that the 30% alcohol extract of bellflower in (1) inhibited the proliferation of prostate cancer cells in the human prostate cancer cell line (LNCap). (3) Therefore, using 30% alcohol extract, normal-butanol (n-butanol) fraction was obtained and it was confirmed that the human prostate cancer cell line (LNCap) inhibited the proliferation of prostate cancer cells. In addition, (4) treatment of an effective compound isolated from bellflower to human prostate cancer cell lines (LNCap, PC-3) to confirm that the proliferation of prostate cancer cells is inhibited, thereby preventing and treating a pharmaceutical composition for prostate disease or prevention of prostate disease And it can be used as a health functional food composition for improvement. |
| priorityDate | 2019-05-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 65.