abstract |
The present invention is metabolically engineered Corynebacterium glutamicum ( Corynebacterium glutamicum ) By introducing a fucosyl lactose transporter to the strain and optimizing the GDP-L- fucose biosynthesis pathway, 2'-fucosyl lactose production is increased It relates to a method for producing 2'-fucosyllactose by using the same for the production of a recombinant microorganism and using the same, according to the present invention, 2'- using a GRAS strain, Corynebacterium glutamicum ( Corynebacterium glutamicum ) strain It is possible to produce fucosyllactose, which is suitable for producing 2'-fucosyllactose for use as food materials and pharmaceutical materials compared to the conventional technology using E. coli, and in the technology using the conventional Corynebacterium glutamicum. It is possible to produce 2'-fucosyllactose with much higher concentration, high yield, and high productivity compared to that. |