http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102265215-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08B13-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5089 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5042 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2866 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-525 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-38 |
| filingDate | 2017-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-102265215-B1 |
| titleOfInvention | Hypromellose acetate succinate powder excellent in dissolved state and production method thereof, and production methods for composition for solid dispersion, coating composition, drug-containing particle, and solid preparation |
| abstract | [Problem] To provide an HPMCAS powder having high solubility when dissolved in a solvent and capable of suppressing the generation of undissolved substances, and a method for producing the same. [Solutions] To provide a hypromellose acetate succinate powder having an average value of the ratio (L/D) of the maximum diameter (L) and the minimum diameter (D) of 2.0 to 3.0. In addition, a dissolution step of dissolving hypromellose in a solvent, an esterification step of obtaining a reaction solution by reacting succinic anhydride and acetic anhydride with the dissolved hypromellose in the presence of a catalyst, and the reaction solution and water It is a precipitation step of precipitating hypromellose acetate succinate ester by mixing, and at least comprising a precipitation step in which the viscosity of the reaction solution before mixing with water is 100 to 200 Pa·s. A manufacturing method is provided. |
| priorityDate | 2016-04-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 192.