http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102264115-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-20 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-111 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-102 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-902 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-22 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-90 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 2019-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-06-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-06-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-102264115-B1 |
| titleOfInvention | Carrier-free multiplex CRISPR/Cas gene editing complex and uses thereof |
| abstract | It relates to a composition for gene editing comprising a carrier-free multiple CRISP/Cas 9 gene editing complex for editing multiple target DNA and uses thereof. According to the gene editing complex according to an aspect, in the formation of a complex with the guide RNA and the intracellular delivery of the guide RNA, even without other cationic polymers or lipid carriers, excellent delivery of the guide RNA in vivo or in vitro compared to the existing method It has activity and effectively enables editing of one or more genes, enabling editing of multiple loci at the same time. In addition, the gene editing complex according to an aspect can effectively inhibit the expression of PD-L1 and PD-L2, and thus induce T cells to produce interferon-γ to effectively kill cancer cells, so it can be usefully used as an anticancer agent. there is an effect |
| priorityDate | 2019-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 588.