http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102252124-B1
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23V2200-314 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23V2002-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2300-00 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K36-185 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23L33-105 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A23L33-105 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-185 |
filingDate | 2019-09-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-102252124-B1 |
titleOfInvention | Composition for improving respiratory diseases using the extract of Picrasma quassioides |
abstract | The present invention discloses a composition for improving pulmonary diseases such as asthma or chronic obstructive pulmonary disease using a bovine extract. Bovine extract inhibits the activation of netosis of neutrophil extracellular traps induced by PMA (phorbol myristate acetate), and proliferation by CSE of NCI-H292 cells, a mucous-producing bronchial epithelial cell line. And its inflammatory cytokine IL-8, inhibiting the proliferation of alveolar macrophages MH-S cells activated by CES and LPS (lipopolysaccaride) and the expression of the inflammatory cytokine MIP-2 Have. In addition, in the respiratory disease mouse model administered with botanical extract, the activity of reducing the total number of BALF cells is similar to that of the group administered with Roflumilast (ROF), which is a positive control. |
priorityDate | 2018-09-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 241.