| abstract |
It relates to miRNA related to epilepsy and its therapeutic agent, diagnostic composition, and use in disease animal models. According to a substance capable of inhibiting miRNA according to an aspect, by increasing the expression of KCNQ2, neuronal excitability related to epilepsy is increased. Since it decreases, it can be usefully used in the treatment of epilepsy, and it can be used not only in a method for diagnosing epilepsy using the same as a biomarker, but also has an effect that can be usefully used in disease animal models. |