http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102237590-B1
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-43518 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-705 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-435 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-435 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
filingDate | 2017-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-04-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-04-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-102237590-B1 |
titleOfInvention | Peptide modulator of purine receptor |
abstract | The present invention relates to medicine and pharmacology, i.e., to biologically active peptides that modulate purine signaling. For these purposes, a peptide having the following amino acid sequence or a sequence having at least 90% homology thereto is proposed: Gly 1 -Tyr 2 -Cys 3 -Ala 4 -Thr 5 -Lys 6 -Gly 7 -Ile 8 -Lys 9 -Cys 10 -Asn 11 -Asp 12 -Ile 13 -His 14 -Cys 15 -Cys 16 -Ser 17 -Gly 18 -Leu 19 -Lys 20 -Cys 21 -Asp 22 -Ser 23 -Lys 24 -Arg 25 -Lys 26 -Val 27 -Cys 28 -Val 29 -Lys 30 -Gly 31 . The peptides in the present invention can be used for the prevention and treatment of diseases mediated by purine receptors. The peptides can be used not only for the development of new drugs based on them, such as analgesics, but also for the investigation of the mechanism of pain development, for the identification and testing of new modulators of the P2X3 receptor. The peptides in the present invention can be produced using chemical synthesis or bioengineering the nucleotide sequence of the corresponding gene. |
priorityDate | 2016-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 150.