http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102235549-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_099e5527e5b580f94c89bdff5de02092 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-65 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6889 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-65 |
| filingDate | 2019-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a6ef3193245634552106d0f33d8d6457 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c8ab42b0daebc705089e71e940c4dc7f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3dbcbe481137d6b1bdcdbc76fdad89bf |
| publicationDate | 2021-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-102235549-B1 |
| titleOfInvention | Novel bio-conjugation kit using bifunctional linker and Cys-tagged SpyTag/Catcher for ADC |
| abstract | As a linker for stable conjugation of antibodies and drugs in the development of ADCs, a new conjugation kit with more stable and high conjugation efficiency is disclosed that improves the disadvantages of the conventional chemical conjugation method and the post-translation conjugation method. The present invention is a conjugation kit between antibodies and drugs for the formation of antibody-drug conjugates (ADC), comprising: a cysteine-tagged (Cys-Tagged) spy tag (SpyTag) oligopeptide; Cysteine-tagged (Cys-Tagged) SpyCatcher protein; And a bifunctional linker conjugated to a thiol group of the cysteine of the spy tag or the spy catcher. |
| priorityDate | 2019-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 125.