Predicate |
Object |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-18133 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-18143 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-18122 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-18132 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-18121 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-3955 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2878 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2827 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2818 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-768 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-768 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-00 |
filingDate |
2014-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2021-03-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate |
2021-03-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
KR-102222157-B1 |
titleOfInvention |
Newcastle disease viruses and uses thereof |
abstract |
Described herein are chimeric Newcastle disease viruses, and compositions comprising such viruses, engineered to express agents of co-stimulatory signals of immune cells. Chimeric Newcastle disease viruses engineered to express antagonists of inhibitory signals of immune cells and compositions comprising such viruses are also described herein. The chimeric Newcastle disease virus and composition are useful for the treatment of cancer. Additionally, described herein are methods of treating cancer comprising administering Newcastle disease virus with an agonist of an agonist of a costimulatory signal of an immune cell and/or an antagonist of an inhibitory signal of an immune cell. |
priorityDate |
2013-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |