http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102217347-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2236-39 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23V2200-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23V2002-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23L33-105 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K36-62 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A23L33-105 |
| filingDate | 2017-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-02-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-02-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-102217347-B1 |
| titleOfInvention | Pharmaceutical composition comprising the extracts of seed of nelumbo nucifera as an effective component for prevention or treatment of thrombosis and health functional food comprising the same |
| abstract | The present invention relates to a pharmaceutical composition and health functional food for the prevention or treatment of thrombosis containing a seed of Nelumbo nucifera extract as an active ingredient, and more specifically, a hot water extract or ethanol extract of lotus It relates to a pharmaceutical composition for preventing or treating/improving thrombosis through potent platelet aggregation inhibition and blood coagulation inhibition using an organic solvent fraction of an ethanol extract or a water residue after the organic solvent fraction as an active ingredient and a health functional food. The lotus extract as an active ingredient of the pharmaceutical composition for preventing or treating thrombosis and health functional food of the present invention is inhibited by the inhibitory effect on the aggregation of platelets, which plays a role in the initiation of thrombus formation along with inhibition of blood clotting-related enzymes and blood clotting factors. At the same time, it exhibits strong antithrombotic activity, does not show any hemolytic activity against human red blood cells, has excellent thermal stability, and shows a loss of blood coagulation factor inhibitory effect and blood clot formation-related enzyme inhibitory effect even in acidic conditions of pH 2 and plasma. Therefore, it is expected that it can be used for the prevention and treatment of thrombosis such as ischemic stroke and hemorrhagic stroke through improvement of blood circulation, and the active ingredient is processed into various forms such as extract, powder, pills, tablets, etc. It is a very useful invention in the pharmaceutical industry and food industry because it has an excellent effect that can be prepared with. |
| priorityDate | 2017-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 107.