| abstract |
The present invention relates to compounds of formula I: [Formula I] Wherein X is N or CR 1 ; Y is N or CR 2 ; R 1 is H, alkoxy, halo, triazolyl, pyrimidinyl, oxazolyl, isoxazole, oxadiazolyl or pyrazolyl; R 2 is H, alkyl, alkoxy or halo; Z is NH or O; R 3 is H, alkyl, alkoxy, halo or triazolyl; R 4 is H or alkyl; R 3 and R 4 together with the atom to which they are attached form a 6-membered aryl ring or a 5- or 6-membered heteroaryl ring; R 5 is pyridyl, pyrazinyl or pyrimidinyl, wherein pyridyl, pyrazinyl or pyrimidinyl is optionally substituted with halo or alkyl; n is 1 or 2. Methods for the preparation of compounds of formula I are also described. The invention also relates to pharmaceutical compositions comprising a compound of formula (I). Methods of using the compounds of the present invention are also within the scope of the present invention. |