abstract |
The present invention relates to a benzamide compound having protein kinase inhibitory activity, a pharmaceutically acceptable salt thereof, and a pharmaceutical composition for the prevention and treatment of diseases caused by abnormal cell growth containing the compound as an active ingredient. The novel compounds of the present invention exhibit an excellent inhibitory effect against PDHK protein kinase, which is a major inducer of diabetes, obesity, and cancer. Therefore, it is induced by abnormal cell growth and metabolism caused by PDHK protein kinase induced by these protein kinases. It is useful as a preventive and therapeutic agent for disease. |