| abstract |
The present invention relates to a medical hydrogel composition, a medical hydrogel, a manufacturing method and use thereof, and a medical hydrogel kit. The medical hydrogel composition includes a first component and a second component; The first component comprises polylysine and polyethylene imine; The second component is 4-arm-polyethylene-succinimidylglutarate, 4-arm-polyethylene glycol-succinimidyl succinate and 4-arm-polyethylene glycol-succinimidyl carbonate (4-arm-polyethylene glycol-succinimidyl succinate). arm-polyethylene glycol-succinimidyl carbonate). The degree of polymerization of the polylysine is 20 or more. The medical hydrogel is formed by reacting the first component with the second component of the medical hydrogel composition. The medical hydrogel kit is composed of the medical hydrogel composition and a buffer solution used to dissolve the components of the medical hydrogel composition. The expansion rate of the medical hydrogel is -10% to 50%, and can be applied to a narrow area where the brain, spine, and peripheral nerves are concentrated. |