http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102201901-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-136 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-4703 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-705 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57438 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6886 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574 |
| filingDate | 2019-01-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-01-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-01-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-102201901-B1 |
| titleOfInvention | SMARCB1 and NUP210, the markers for diagnosing liver cancer, and method for predicting liver cancer using the marker |
| abstract | The present invention relates to SMARCB1 and NUP210, which are markers for diagnosing liver cancer, and a liver cancer prediction method using them, specifically SMARCB1 overexpressed in liver cancer cells binds to an enhancer of NUP210, upregulates NUP210, and enhances It was confirmed that NUP210 bound to SMARCB1 and P300 acted as a scaffold to promote the expression of cancer-causing genes by enhancing the binding of SMARCB1 and P300 and their mutual binding, and chromatin affinity. Therefore, SMARCB1 and NUP210 were diagnosed with liver cancer. It can be used as a marker, and can be usefully used for diagnosing liver cancer or screening liver cancer therapeutics by measuring protein binding and chromatin affinity between SMARCB1, NUP210 and P300. |
| priorityDate | 2019-01-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 239.