Predicate |
Object |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-52 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4703 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-705 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6811 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
filingDate |
2019-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2020-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate |
2020-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
KR-102194644-B1 |
titleOfInvention |
Novel fusion protein and pharmaceutical composition for preventing or treating cancer comprising the same |
abstract |
The present invention relates to a fusion protein comprising an extracellular domain of Lrig-1 (leucine-rich and immunoglobulin-like domains 1) protein and an immunoglobulin Fc region. The fusion protein provided by the present invention interacts with a ligand for the Lrig-1 protein present in effector T cells, and regulates T cells (regulatory T cells, Tregs) containing the Lrig-1 protein on the surface. cell) and effector T cells, thereby inhibiting the activity of regulatory T cells and maintaining or increasing the activity of effector T cells, thereby effectively inhibiting the growth of solid cancer cells, especially among cancer cells. |
priorityDate |
2018-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |