http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102193405-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-48 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0606 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0735 |
| filingDate | 2019-06-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-102193405-B1 |
| titleOfInvention | Method of selective elimination of culture-adapted pluripotent stem cells |
| abstract | The present invention relates to a method for selective apoptosis of culture-adapted undifferentiated pluripotent stem cells. Specifically, as the later stages of subculture, human embryonic stem cells (hESCs) have increased resistance to YM155, a compound that can selectively apoptosis only undifferentiated pluripotent stem cells depending on the expression of BCL-xL protein. The selective apoptosis method of culture-adapted undifferentiated pluripotent stem cells including the step of treating BCL-xL protein inhibitors by confirming that protein inhibitors can selectively kill only hESCs resistant to YM155 is the development of stem cell therapeutics. And it can be usefully used in application. |
| priorityDate | 2018-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 150.